nikoliskey sign

Nikolsky's sign involves the superficial layers of skin slipping free from the lower layers with slight pressure.
Reference from A.D.A.M.
Back to TopConsiderations
A positive Nikolsky's sign is present in the scalded skin syndrome (caused by staphylococcal infection) and in a slightly different form in toxic epidermal necrolysis (a severe drug reaction). It may also be seen in pemphigus vulgaris (a disease which causes blisters to form on the skin).
In each of these diseases, the skin is loosened and when rubbed, slips free just as the skin on a blanched tomato or peach would. The area beneath is pink and moist and may be very tender.
Back to TopCommon Causes
Scalded skin syndrome (also called Ritter disease)
Toxic epidermal necrolysis
Pemphigus vulgaris

Hmophilous inflenza

Mee's line (Arsenic poisoning)

Mee's line (Arsenic poisoning)

Wood's lamp excamination

A Wood's light is an ultraviolet used to reveal hypopigmented patches on skin.
It is helpful in the diagnosis of the hypopigmented patches of tuberous sclerosis, particularly in asymptomatic parents.

Wood's lamp lesion

Red fluorescence with Wood's lamp on psoriatic skin. (a) Heterogeneous red fluorescence within a psoriatic plaque on a leg; (b) standard flash photograph of the same plaque.

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